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Three antidepressants have proved to be ineffective: amoxapine, trazodone, and bupropion. Paroxetine and sertraline seem to induce less of the paradoxical effect in patients with panic disorder, according to the results of multicenter trials. To minimize the paradoxical activating effect, Dr. Reiman recommended starting patients on an unusually low dose and increasing the dose slowly. COPYRIGHT 2002 International Medical News Group COPYRIGHT 2008 Gale, Cengage Learning. loans in northern virginia loan amoritization car loan title utah airport business loans loan originator and ft walton beach